IVT Reaction
In vitro transcription creates mRNA oligonucleotides from pDNA templates in a one-pot reaction precisely controlled for maximum efficiency. Other enzymatic steps can be performed at this time if desired, such as 5’ capping. Additional enzymatic processing steps may be added to the “one-pot” reaction but increase complexity and quality control requirements. Aldevron can fulfill your IVT enzyme needs and offer comprehensive testing and quality oversight to match your scale. Data ecosystem management with IDBS Polar Biopharma Lifecycle Management platform can enable process standardization by breaking down data silos.
The Genedata Biopharma Platform streamlines the entire mRNA development workflow, including in vitro transcription, by requesting and registering all expression batches and sequence or capping modifications as part of a fully automated and barcoded process.