Formulation and Bulk Fill
Perform in-depth analysis with a SCIEX ZenoTOF 7600 mass spectrometer. Purified mRNA is stabilized in buffers for storage and shipping, concentrated and filtered to remove impurities.
mRNA solutions are divided into smaller volumes and frozen, ready for transfer to analytical and CMC laboratories. Developing freeze/thaw processes that preserve nanoparticles intact is important for scaling to production.
The Genedata Biopharma Platform streamlines the entire mRNA development workflow. This includes formulation with different delivery systems such as lipid nanoparticles (LNPs). Automate analysis of LC-MS, UV, qPCR, fluorescence and other CQA data on final product purity and identity. Track different formulations or products along with their associated properties and performance.