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ImageXpress® Micro 4 High-Content Imaging System

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Configurable, high-throughput widefield imaging solution for an incredible range of assays

Widefield imaging for basic research through to high-content screening

The ImageXpress® Micro 4 High-Content Imaging System is a high-throughput, widefield imager that can acquire images of whole organisms and cellular or intracellular events. It features proprietary fast frame rate technology, allowing for the capture of fast biological processes such as calcium oscillations in cardiomyocytes. It is highly configurable and adaptable to changing research needs. Available options include confocal, brightfield, phase contrast, liquid handing, and environmental control.

  • Support many cellular assays

    Image an incredible range of assays with various user-changeable filter cubes, 1-100x objectives, environmental control, fluidics option, and many sample formats including atypical plates for 3D assays.

  • Analyze images of more applications

    A selection of feature-rich turnkey application modules is available with MetaXpress® software. For the development of novel assays, we offer an optional custom analysis module.

  • Tailor the system to meet your needs

    The imager is a highly flexible solution, you can add or change many of the components as your research priorities change. Examples include enhance light engines and automation.

 

Features

  • Multiple imaging modes

    The system offers fluorescence, widefield, colorimetric, phase contrast, and brightfield label-free imaging.

  • Upgradeable to confocal

    The system can be upgraded to include the proprietary AgileOptix™ technology for accurate 3D volumetric analyses.

  • Wide dynamic range

    Low and high intensity signal quantification in a single image with >3 log dynamic range intensity detection.

  • High speed image acquisition

    Using 4x magnification with a 1536-well plate, 225K wells per day can be acquired. Greater than a million wells per week can be imaged.

  • Optional environmental control

    Temperature, humidity, and CO2 control for multi-day live-cell imaging or fast kinetic studies are available.

  • Large magnification range

    Air and oil immersion objectives ranging from 1x to 100x are available for installation into the 4-position objective changer.

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Phenotypic characterization of toxic compound effects on cardiomyocytes derived from induced pluripotent stem cells
Assess cardiotoxicity effects using automated imaging
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Phenotypic Assessment of Toxicity using Human Hepatocyte Co-Culture Model | Molecular Devices
The phenotypic assays have been developed for assessing multi-parameter readouts of general and mechanism-specific hepatotoxicity. Explore this poster for more information.
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Morphometric characterization of cancer spheroid cultures using confocal imaging and 3D image analysis | Molecular Devices
Learn how confocal imaging can be used to improve performance and throughput of high-content assays with 3D cell models for compound screening and evaluation of anti-cancer drugs.
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Measure Cell Migration using Automated Cell Imaging and Analysis | Molecular Devices
Effectively image and analyze cell migration using a scratch assay or a dissolvable biocompatible gel.
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Increase accuracy and efficiency of cytotoxicity using EarlyTox Live/Dead Assay
This application note describes the use of the EarlyTox Live/Dead Assay Kit in conjunction with the ImageXpress Micro High-Content Imaging System & MetaXpress and high-content imaging system.
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Assessment of neurotoxicity and neuronal development using induced pluripotent stem cell-based neurite outgrowth assay | Molecular Devices
This application note describes about the neurotoxicity & neuronal development by using pluripotent stem cell-based neurite outgrowth assay which evaluate & prioritize chemicals for their neurotoxicity potential.