Mica WideFocal Live Cell Microhub Automated Microscope
Combine widefield and confocal imaging in an incubating environment and simplify advanced live cell and fluorescence imaging. Extensive intelligent automation, AI-supported analysis, and an easy-to-use interface help you achieve expert microscopy results without all the training.
Perform long-term live cell experiments up to 4x faster than traditional widefield systems, capturing events that may previously have been missed. Easily get quality images as Mica automatically corrects the focus during experiments. Minimise phototoxicity and maintain optimal cell health with full environmental control.
Ideal for long-term and dynamic live cell studies of organoids, spheroids, and 3D cultures.
MICA BENEFITS:
ACCESS FOR ALL: Mica requires minimal technical input and gives consistent results every time, so all lab members can leverage microscopy to make more discoveries.
NO CONSTRAINTS: Visualize in widefield and switch effortlessly to confocal without ever moving your sample. Get true simultaneous capture of up to four labels without spatiotemporal mismatch – at near-physiological conditions for live cells, or with fixed samples.
RADICALLY SIMPLIFIED WORKFLOWS: Intelligent automation and AI-supported analysis of diverse samples, such as tissues on slides or well plates, enable greater efficiency and a faster track to publication.
Target application: Advanced live-cell imaging with confocal capability
Imaging modes
- Widefield fluorescence
- Point scanning confocal with 4 laser lines (405, 488, 561, 638 nm)
- Includes THUNDER computational clearing and LIGHTNING deconvolution for enhanced image quality
- FluoSync™ widefield and confocal detectors for simultaneous 4-label imaging
- Transmitted light microscopy
- Supports Z-stacks, time-lapse
Achieve physiological-like conditions throughout your live cell experiments
- The entire encapsulated inner sample space of Mica can be climate controlled (temperature, CO2, and humidity regulation), offering ideal conditions for live cell observation.
- Equipment for Hypoxia experiments is available optionally.
- Flexibility in sample use with slides, petri dishes, chambered slides and well plates.
| Fixed Samples | Yes |
| Fixed + Live Cells | Yes |
| Integrated Modulation Contrast (IMC) | Yes |
| Brightfield Contrast in RGB or Grayscale Mode | Yes |
| LED Incident Fluorescence Illumination | 368 nm, 470 nm, 555 nm, 625 nm |
| Widefield FluoSync Detector Type | CMOS |
| No. Widefield FluoSync Label Simultaneous Imaging | 4 |
| Confocal Illumination Laser Diodes | 405 nm, 488 nm, 561 nm, 638 nm |
| Confocal FluoSync Detector Type | HyD FS |
| No. Confocal FluoSync Label Simultaneous Imaging | 4 |
| Included Objectives | PL FLUOTAR 1.6x/0.05, PL FLUOTAR 10x/0.32 |
| Optional Recommended CS2 Objectives | 20x, 40x W, 40x Oil, 63x W, 63x Oil |
| Immersion Dispension (closed loop water dispenser) | Yes |
| Maximum Live Cell Temperature | 45 °C |
| Maximum Live cell CO2 humidity | 10 % |
| Optional Hypoxia Upgrade Maximum Temperature | 45 °C |
| Optional Hypoxia Upgrade Maximum O2 Humidity | 10 % |
| Optional Hypoxia Upgrade Maximum CO2 Humidity | 10 % |
| Adaptive Focus Control (AFC) | Reflection-based |
| Image-Based Autofocus | transmitted light, fluorescence images |
| Autofocus Combined with AFC | Yes |
| Includes THUNDER methods | Instant Computational Clearing (ICC), Small Volume Computational Clearing (SVCC), Large Volume Computational Clearing (LVCC) |
| Supplied LIGHTNING Packages | Basic |
| Optional LIGHTNING Packages | Expert |
Mica Core
11525700
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Mica WideFocal Live Cell
11889179
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Mica High Power WS and Analysis Package
11525738
1
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HP E32K G5 31.5 UHD IPS"
11533649
1
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Aivia Go 6 Months
27100031
1
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Microscope Objective HC PL FLUOTAR L 20x/0.60 motCORR
11506438
1
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Microscope Objective HC PL APO 63x1,2 W motCORR CS2
11506427
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DSE powered by Aivia
11640663
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Advanced application training one day
9I_CM_APPLIC1
1
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Service Installation
9I_CM_MICA_E
1
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Microscopy Training Basic
9T-CM-APP_BASIC
1
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Keyboard US ;USB Hub
11600220
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Cordless Keyboard+Mouse US
11533582
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Okolab Click-In,standard & chamber slide
11525712
1
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